• Interaction Score: 5.3

    Interaction Types & Directionality:
    antagonist (inhibitory)

    Interaction Info:


    Sources:
    DTC

  • Interaction Score: 0.25

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    combination therapy ABT-737 + BEZ235
    Evidence Type Actionable
    Approval Status Preclinical - Cell line xenograft

    PMIDs:
    27974663


    Sources:
    JAX-CKB

  • Interaction Score: 0.19

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    combination therapy Oxaliplatin + ABT-737
    Indication/Tumor Type Advanced Solid Tumor
    Response Type sensitive

    PMIDs:
    21468686


    Sources:
    JAX-CKB

  • Interaction Score: 0.18

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    combination therapy ABT-737 + BEZ235
    Indication/Tumor Type triple-receptor negative breast cancer
    Response Type predicted – sensitive

    PMIDs:
    27974663


    Sources:
    JAX-CKB

  • Interaction Score: 0.07

    Interaction Types & Directionality:
    n/a

    Interaction Info:
    combination therapy Oxaliplatin + ABT-737
    Indication/Tumor Type Advanced Solid Tumor
    Response Type sensitive

    PMIDs:
    21468686


    Sources:
    JAX-CKB